Category: Advanced Toxicology

Unit III Case Study
Mr. Jones, age 37, is the CEO and owner of Jones Farm. He inherited the farm from his father and resides in the family
home there with his wife Jane, age 35, and 4-year-old daughter, Angel. The Jones Farms is a large producer of various
fruits, vegetables, and grains. Through trial and error, Mr. Jones, found a local company that produces an insecticide
containing chlorpyrifos to be the most economical and effective insecticide for his crops. This insecticide has been used for
almost 7 years at the farm for every crop produced. With easy access to this insecticide on the farm, it has been commonly
used for pest control within their large home as well.
Being proud owners of the crops grown on the farm, the Jones family often take advantage of the fresh fruits and vegetables
available for their own table. Their consumption of the farm’s harvest has increased since the COVID-19 pandemic has
negatively impacted their finances. The Joneses and their toddler, Angel, enjoyed fresh fruit and vegetables from the farm
throughout the day.
Mr. and Mrs. Jones have recently grown increasingly concerned about their daughter’s development. They have noticed that
Angel seems to still be having a hard time with potty training despite being 4 years old. She has not picked up on basic
colors and animals sounds that her preschool peers have almost mastered. Angel’s preschool teacher has mentioned that
all children learn at their own pace but has voiced another concern with Mr. and Mrs. Jones regarding Angel’s motor skills
development. While Mr. Jones appears relatively healthy, both he and Mrs. Jones frequently experience migraines which
they attribute to the stress of everyday life and finances. Mrs. Jones often experiences nausea and even vomiting along with
migraines. 
After reading the case study and researching chlorpyrifos, respond to the following discussion points:
1. Identify how the family members could have been exposed to chlorpyrifos.
2. Identify the exposure pathway of chlorpyrifos. 
3. What organ systems were affected by the chemical? 
4. What observable acute and chronic effects could be produced from exposure to the chlorpyrifos? What effects were
observed in the case study? How and why are the effects different in the individuals? (i.e., what individual profile
factors can affect toxicity?)
5. How could exposure to the chemical be avoided? 
The paper must have a minimum of two pages, not counting the title and reference pages. Utilize at least three credible
references, one of which may be the textbook, and one of which must come from the CSU Online Library.
All sources used, including the textbook, must be referenced. Paraphrased and quoted material must have accompanying  citations. Adhere to APA Style when constructing this assignment, including in-text citations and references for all sources
that are used. Please note that no abstract is needed.